
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

A garbage bag leads police to a child's killer.