
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

A girl who is abducted and then released soon afterward uses her knowledge of forensics to lead police to the kidnapper.

Car with three Secret Service agents collides with local deputy's car; investigation launched into who was responsible for the deadly car accident finds two very different conclusions.