
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

The body of an insurance assessor is found in a river in Tampa, Fla.; a unique murder weapon and blatant clues lead the police straight to her careless killer.

When prison guard Donna Payant's body is discovered at a landfill, a medical examiner uses a "signature" clue to link her death to a murder the same examiner investigated 10 years earlier.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

A woman is abducted and a month later found dead, then a tip leads investigators in the right direction.