
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

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Investigators search the world of high rollers and offshore betting to solve the first triple homicide in Verona, Wisc.
Police search every apartment building in town when the body of a young girl found on an isolated farm holds a set of keys but no ID.
A man denies killing a pedestrian in hit-and-run, claiming he sold the car in question; authorities track down the car to find critical evidence.
Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.