
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

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With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.
The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.
Tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.
In 1984 police failed to convict the murderer of a college student; new technology may finally help the police to catch her killer.