
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Romanian archbishop Valerian D. Trifa, living in the U.S., is accused of being a Nazi war criminal, and forensic experts find evidence on an incriminating, 40-year-old postcard.

A family vacation turns into a terrifying search for a missing wife and baby, then becomes a manhunt for a killer who committed a horrific crime.

When a doctor's wife disappears, investigators use concrete from the doctor's yard and the recollections of a child to determine what happened.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.