
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A family suspects their teenage daughter's new friends were involved in her disappearance.

Detectives learn that a genetic disorder caused the deaths of a woman's children, resulting in an overturned conviction.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.