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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S4, EP3 "Ultimate Betrayal"
A 1995 fire razes the mansion of a Kansas doctor, killing two of her three children; disturbing accounts from an ex-husband lead investigators to believe the doctor set the blaze herself.
S6, EP19 "Pure Evil"
The search for the killer of two teenagers in Texas shows a behavioral study on how most serial killers also have a history of abusing animals.
S4, EP2 "The Killing Room"
A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.
S6, EP22 "Punch Line"
Despite a patient's claim that the cut to his hand had been caused by a dumpster, the doctor treating the injury recognizes it as something else -- and soon becomes the chief witness in a murder case.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.