
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A young woman goes missing without leaving many clues, but the advanced technology on offer makes it possible for cat hairs and insects to help build an image of the abductor.

Investigators solve the 1988 murder of a drifter in Southern California by examining a species of fly found near the body.

The investigation of a murder case in New Jersey is stalled until a similar attack occurs on a state trooper in Maine.

Following an outbreak of thyrotoxicosis in Sioux Falls, S.D., thought to have come from contaminated meat, the Department of Agriculture conducts a review of the use of thyroid hormones in animal products.