
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

A garbage bag leads police to a child's killer.

An investigation into the disappearance of a young woman uncovers a tooth that helps police solve a crime without a body.