
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

The investigation of a murder case in New Jersey is stalled until a similar attack occurs on a state trooper in Maine.

Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.

When a 9-year-old girl vanishes on her way to school, the entire community helps with the search; detectives believe her mother may be involved, and a hidden fingerprint seals the case.

A masked gunman kills two members of a family and wounds two others after they interrupt his burglary at their upscale suburban home.