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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S13, EP41 "Shoe-in for Murder"
Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.
S7, EP33 "Paintball"
When 15 year-old Marlene Miller was murdered, it would take 24 years and several retrials before forensic scientists discovered the evidence to bring her killer to justice.
S13, EP49 "Pet Rock"
A quiet waitress who hasn't been to work in two days vanishes without a trace; police suspect a date gone wrong.
S8, EP4 "Within Arm's Reach"
A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.