
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

With children dying at an alarming rate at a Texas hospital, authorities narrow down their probe to one nurse, but the murder weapon remains elusive.

A wax bullet, white blanket and olive colored carpeting tell a lot about the murder of a young woman found in a ravine.

Police charge Alan "The Zenith Man" Ridley with murdering his wife, Virginia, but following an autopsy, medical detectives believe he may not have killed his wife after all.

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.