
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A son who is convinced of his mother's innocence in the death of his father enrolls in law school to try and clear her name.

The assistant manager of the restaurant had been stabbed to death; police knew why he'd been killed: $8,000 was missing from the safe. As to who was responsible, his family and friends couldn't even imagine who'd want to hurt him.

Blood spatter analysis and an investigation lead police to the truth when a pregnant woman is found dead in her home.

Florida authorities rely on DNA evidence to try to nail the killer of a woman who was abducted from her late-night job at a convenience store, raped and strangled.