
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A bag full of evidence recovered from an iced-over river helps to reveal the murderer of a businesswoman in her own shop.

New York police hunt the Zodiac killer after a series of deadly attacks.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

A woman is killed weeks before testifying against the man who sexually assaulted her.