
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Investigators look into the shooting death of Russ Stager, a popular gym teacher, and discover that his death was not an accident; a message the victim recorded before his death reveals a story of greed.

When murder strikes a young girl, police quickly make an arrest, but cutting-edge technology from NASA proves they have the wrong suspect behind bars.

Romanian archbishop Valerian D. Trifa, living in the U.S., is accused of being a Nazi war criminal, and forensic experts find evidence on an incriminating, 40-year-old postcard.

When two men appear to die of heart disease six years apart, police notice they have one thing in common, they were each married to the same woman.