
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

Weed analysis and photogrammetry are used to help solve the 1995 murder of a California teenager is found dead after disappearing from her home.

When police recover the submerged car of a missing man, they find no body; the investigation that follows uncovers a deadly obsession and the motive for murder.