
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

Investigators see through a killer trying to cover his tracks by staging the crime scene to learn what really happened.

When friends see a woman in the back of a car flailing her arms and screaming, they assume she is having fun, but when they later come upon a jacket and a pool of blood, they realize they witnessed an abduction in progress.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

An attack on a couple's home leaves the husband dead, the wife gravely injured and their son as a prime suspect; hundreds of miles away, a DNA sample may lead to the killer.