
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

DNA profiling reveals clues leading to a killer's identity 20 years later.

When the decomposed body of a young girl is discovered, police have no clues to her identity, but days earlier, a stabbing victim told them she thought she might have witnessed a murder.

When a man dies after falling down the stairs, a witness says one thing and the evidence says another.

With children dying at an alarming rate at a Texas hospital, authorities narrow down their probe to one nurse, but the murder weapon remains elusive.