
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A woman who appeared to have taken her own life told her sister that, if anything were to happen to her, there was a note in the china cabinet.

A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.

When an aspiring model turns up dead, police suspect her boyfriend. But must dig deeper for clues when he is cleared.

When a sexual predator murders two young boys in Nebraska, an obscure style of rope and forensic analysis lead to his arrest and conviction.