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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S13, EP34 "Sign of the Crime"
Two women who lived in the same apartment complex were brutally murdered; the similarities of the crime scenes led police to believe they were dealing with a serial killer who hated women, and they had to find him before he struck again.
S3, EP12 "Broken Bond"
A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.
S3, EP1 "Without a Trace"
Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.
S12, EP20 "All Butt Certain"
A young girl beaten after watching her grandmother killed, identifies the wrong person; years later she tries to change her statement.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.