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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S10, EP21 "The Separation Agitation"
Howard and Bernadette struggle to leave Halley in day care; Bert introduces the gang to his new girlfriend, Rebecca.
S10, EP22 "The Cognition Regeneration"
Leonard is less than thrilled when Penny considers accepting a job offer from Zack, her ex-boyfriend.
S10, EP23 "The Gyroscopic Collapse"
After celebrating the completion of the top-secret Air Force project, Leonard, Sheldon and Wolowitz get an unwelcome surprise; Amy receives an offer for a summer position as a visiting researcher.
S6, EP13 "The Bakersfield Expedition"
As the guys don costumes and go on a road trip to a comic book convention, the ladies decide to stay home and try to interpret a comic book.
S10, EP20 "The Recollection Dissipation"
Sheldon pushes himself to the limit when he collaborates on projects with Leonard and Wolowitz as well as Amy on the same day; Bernadette nears the end of her maternity leave and must return to work.
S10, EP19 "The Collaboration Fluctuation"
Leonard, Penny and Raj settle into their new living arrangement; Sheldon expresses interest in Amy's work.
S10, EP18 "The Escape Hatch Identification"
Leonard and Penny offer Sheldon's old room to Raj after he moves out of his apartment.
S10, EP17 "The Comic-Con Conundrum"
Cut off from his father's fortune, Koothrappali appoints Sheldon to help him get out of debt; Penny considers joining Leonard at Comic-Con.