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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP24 "The Roommate Transmogrification"
Bernadette gets her Ph.D., inspiring the guys to tease Wolowitz about his lack of a doctorate; Raj becomes Sheldon's roommate.
S1, EP5 "The Hamburger Postulate"
Leonard, realizing his pursuit of Penny is fruitless, has an unexpected encounter with a fellow scientist (Sara Gilbert).
S12, EP2 "The Wedding Gift Wormhole"
Sheldon and Amy go crazy trying to figure out what "perfect gift" Leonard and Penny gave them for their wedding; Koothrappali decides to settle down and asks his father to arrange a marriage for him.
S12, EP3 "The Procreation Calculation"
Life gets complicated when Stuart starts bringing his new girlfriend home; Penny and Leonard talk about starting a family; Koothrappali explores an arranged marriage.
S12, EP1 "The Conjugal Configuration"
Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.
