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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP14 "The Thespian Catalyst"
Sheldon takes acting lessons from Penny in hope of becoming a better teacher; Koothrappali fantasizes about his friend's girlfriend.
S4, EP15 "The Benefactor Factor"
A wealthy donor makes Leonard question what he is willing to do for science.
S4, EP16 "The Cohabitation Formulation"
Wolowitz considers taking things with Bernadette to the next level; Leonard and Raj's sister rekindle their relationship.
S4, EP17 "The Toast Derivation"
Sheldon is upset when he realizes Leonard is the center of their group of friends.