
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

When competitors Pemberton and Campbell charm America on a publicity tour, Sheldon and Amy try to win over Nobel laureates Kip Thorne, George Smoot and Frances Arnold; Halley's fear of the dark leads to opportunity and conflict.

Raj faces deportation if he does not find a job; Leonard and Penny deal with Howard as a third wheel.

The weight of winning a Nobel Prize weighs heavy on Amy's shoulders; Koothrappali and Wolowitz try to relive the good old days after Wolowitz buys a scooter that looks like the one he had years ago.

Sheldon seeks revenge on his nemesis, Wil Wheaton; Wolowitz wants Penny to set him up with one of her friends.