
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

Leonard keeps an affair a secret from Sheldon, Howard and Raj.

Sheldon's interview with the FBI jeopardizes Wolowitz's security clearance.

While the guys camp out for a long-awaited movie screening, Penny and Bernadette invite Amy to her first slumber party.

Penny asks Leonard to lie to her father (Keith Carradine); Howard, Raj and Bernadette pull an all-nighter at a telescope.