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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S2, EP8 "The Lizard-Spock Expansion"
Leonard inadvertently steals away the new woman Wolowitz thinks is the love of his life.
S2, EP9 "The White Asparagus Triangulation"
Sheldon is thrilled when Leonard starts dating a woman who meets Sheldon's stringent standards.
S2, EP10 "The Vartabedian Conundrum"
Leonard asks Penny for advice when his new relationship starts moving too fast.
S2, EP12 "The Killer Robot Instability"
When Penny's comment about Wolowitz's love life sends him into a depressed stupor, his friends lose their most important teammate in an upcoming fighting-robot competition.
S7, EP9 "The Thanksgiving Decoupling"
When the gang decides to spend Thanksgiving at Mrs. Wolowitz's house, Sheldon protests; Leonard and Penny deal with an error from her past.
S7, EP8 "The Itchy Brain Simulation"
When a mistake comes to light, Sheldon makes Leonard walk a mile in his shoes; Penny decides to confront Raj's ex.
S7, EP7 "The Proton Displacement"
When Professor Proton asks Leonard for help with an experiment, Sheldon retaliates by befriending Proton's rival, Bill Nye.
S7, EP6 "The Romance Resonance"
Sheldon's latest scientific breakthrough leaves him feeling like a fraud; a romantic gesture between Howard and Bernadette causes Penny to up her game with Leonard.