
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

Penny's home business turns into a complete nightmare when Sheldon takes over.

Penny develops a rivalry with a sexy new female neighbor who threatens her position as queen bee of the building.

Wolowitz and Leonard decide to check out a local bar on Ladies' Night.

Koothrappali and Leonard take Wolowitz to Las Vegas; Sheldon is forced to bunk with Penny when he gets locked out of his apartment.