
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

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Leonard has minor surgery on his nose, causing Sheldon to overreact; Bernadette and Howard work on their marriage.
Sheldon says goodbye to Fun With Flags; Howard, Leonard and Raj look through their dead professor's research; Bernadette learns her co-workers' true feelings.
When the guys agree to do something the girls like, Sheldon and Leonard end up having a confrontation.
Sheldon and Amy try to use math to eliminate wedding planning stress; Koothrappali "breaks up" with Wolowitz after realizing he is hurting his confidence.