
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

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While Leonard prepares for a three-month science expedition, he and Penny re-evaluate their feelings for each other.
After tampering with Sheldon's Arctic-expedition data, the guys follow him back to Texas, which threatens Leonard's chances for romance with Penny.
Penny and Leonard try to recover from an awkward hookup; Howard and Sheldon make a high-stakes bet.
Howard and Raj hit a Goth nightclub to meet women; Sheldon tries chocolate-based behavior modification on Penny.