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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S2, EP8 "The Lizard-Spock Expansion"
Leonard inadvertently steals away the new woman Wolowitz thinks is the love of his life.
S2, EP9 "The White Asparagus Triangulation"
Sheldon is thrilled when Leonard starts dating a woman who meets Sheldon's stringent standards.
S2, EP10 "The Vartabedian Conundrum"
Leonard asks Penny for advice when his new relationship starts moving too fast.
S2, EP11 "The Bath Item Gift Hypothesis"
Penny starts dating Leonard's handsome colleague; Leonard and his friends are tortured by Sheldon's obsession with gift-giving etiquette.
S11, EP13 "The Solo Oscillation"
Sheldon kicks Amy out to work solo; Amy and Leonard bond during a series of science experiments; Bert replaces Wolowitz in the band; Sheldon finds Penny a surprising source of scientific inspiration.