
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

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Sheldon and Amy visit Penny and Leonard after the holidays and tell them about their terrible trip to Texas.
Penny thinks Leonard is taking her for granted and decides to go on a spa weekend with Amy; Wolowitz and Koothrappali try to fix a squeaky floorboard in the baby's room.
Penny's first date with Leonard goes awry; Penny finds Sheldon to be an unwilling confidant.
After seeing Penny with a handsome new guy, Leonard rushes into a rebound relationship with Sheldon's nemesis, Leslie Winkle.