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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S5, EP6 "The Rhinitis Revelation"
Sheldon finds himself competing with the gang for his mother's (Laurie Metcalf) attention when she visits.
S5, EP8 "The Isolation Permutation"
Amy is devastated when Penny and Bernadette shop for wedding dresses without her.
S7, EP14 "The Convention Conundrum"
Unable to get Comic-Con tickets, Sheldon tries to hold his own convention and ends up spending a wild evening with James Earl Jones; the ladies try to act maturely.
S4, EP4 "The Hot Troll Deviation"
An embarrassing secret of Wolowitz's is revealed; Raj and Sheldon get into a war at work.
S5, EP5 "The Russian Rocket Reaction"
Wil Wheaton invites Leonard and Sheldon to a party at his house; Howard receives an opportunity.
S5, EP4 "The Wiggly Finger Catalyst"
Raj wants a girlfriend, so Penny introduces him to a woman he can communicate with.
S5, EP3 "The Pulled Groin Extrapolation"
Amy and Leonard try to become better acquainted; Bernadette, Howard and Mrs. Wolowitz spend the weekend together.
S5, EP2 "The Infestation Hypothesis"
Amy is caught in the middle when Penny and Sheldon get into an argument over a pre-owned chair; Leonard tries to make his long-distance relationship more exciting.