
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

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Wolowitz's return from space isn't all he expected; game night becomes a gender war.
A game threatens Sheldon's relationship with Stephen Hawking; Penny secretly signs up for a college class.
Bernadette wants Wolowitz to move out of his mom's house; Sheldon is caught in the middle of Amy and Wil Wheaton's argument.
Raj and Howard try to figure out why Sheldon disappears at 2:45 every afternoon; jealousy arises in Penny and Leonard's relationship.