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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S5, EP8 "The Isolation Permutation"
Amy is devastated when Penny and Bernadette shop for wedding dresses without her.
S5, EP10 "The Flaming Spittoon Acquisition"
Sheldon is jealous when Stuart (Kevin Sussman), a guy from the comic book store, asks Amy out on a date.
S5, EP22 "The Stag Convergence"
Knowledge of Howard's sexual history makes Bernadette reconsider their future together.
S5, EP23 "The Launch Acceleration"
Wedding plans are jeopardized when NASA reschedules Howard's mission; Leonard says something in the bedroom that surprises Penny.