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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S11, EP4 "The Explosion Implosion"
Wolowitz and Sheldon bond over having disappointing fathers; Leonard is disturbed when his mother finds a new best friend in Penny.
S11, EP5 "The Collaboration Contamination"
Sheldon and Koothrappali confide in Bernadette when they can't handle Amy and Wolowitz working together; Penny and Leonard learn a secret from an unlikely source about dealing with Sheldon.
S3, EP23 "The Lunar Excitation"
Raj and Howard set up an online dating profile for Sheldon and find the perfect woman.
S12, EP4 "The Tam Turbulence"
When Sheldon won't tell anyone why he's never mentioned Tam, his childhood best friend, Leonard takes matters into his own hands; Bernadette and Penny take Raj's fiancee out to dinner to get to know her.