
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

Koothrappali is worried people won't take him seriously in his own field after publishing a paper that suggests he may have discovered alien life; Leonard wants to be the principal investigator on a plasma physics study.

Sheldon teaches Leonard how to understand football; a kite-fighting incident threatens Howard and Raj's friendship.

While facing dramatic changes in his relationship with Amy, Sheldon pushes Penny and Leonard to choose a wedding date.

Sheldon struggles to understand what is going on with Amy; Penny must decide if she can get past Leonard's bad behavior.