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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S11, EP20 "The Reclusive Potential"
A brilliant but reclusive scientist, Doctor Wolcott, invites Sheldon to his cabin in the middle of nowhere; Penny and Bernadette improvise after Amy doesn't like the tame bachelorette party they planned for her.
S2, EP4 "The Griffin Equivalency"
Raj gets an inflated ego and makes a play for Penny after being referenced in a magazine article.
S11, EP13 "The Solo Oscillation"
Sheldon kicks Amy out to work solo; Amy and Leonard bond during a series of science experiments; Bert replaces Wolowitz in the band; Sheldon finds Penny a surprising source of scientific inspiration.
S11, EP14 "The Separation Triangulation"
Koothrappali learns the woman he's dating has a very upset husband; Sheldon rents his old room for a quiet place to work.
