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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP10 "The Alien Parasite Hypothesis"
Amy realizes she has feelings for Penny's ex; Koothrappali and Wolowitz try to prove who would be a better superhero.
S4, EP11 "The Justice League Recombination"
The guys try to bond with Penny's new boyfriend through a costume contest.
S7, EP12 "The Hesitation Ramification"
As Leonard tries to help Penny with a disappointment, Penny asks him a bold question about their relationship; Sheldon wants to learn how to be funny.
S4, EP2 "The Cruciferous Vegetable Amplification"
Realizing he will not live long enough to download his consciousness into a robot body, Sheldon tries to extend his life span.
S8, EP16 "The Intimacy Acceleration"
Penny and Sheldon design an experiment -- as a joke -- to make participants fall in love; Howard and Bernadette get into trouble at the airport.
S8, EP15 "The Comic Book Store Regeneration"
While the gang waits for the reopening of Stuart's comic book store Wolowitz gets some shocking news; Penny has trouble taking her own advice; Leonard and Raj think they spot Nathan Fillion at a restaurant.
