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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S11, EP24 "The Bow Tie Asymmetry"
When Amy's parents and Sheldon's family arrive, everybody is focused on making sure the wedding arrangements go according to plan -- everyone except the bride and groom.
S12, EP1 "The Conjugal Configuration"
Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.
S3, EP6 "The Cornhusker Vortex"
Sheldon teaches Leonard how to understand football; a kite-fighting incident threatens Howard and Raj's friendship.
S3, EP7 "The Guitarist Amplification"
Sheldon tries to make peace when Leonard and Penny get into an argument.
S11, EP23 "The Sibling Realignment"
Sheldon's mother won't attend his wedding unless he invites his brother; the Wolowitz kids inadvertently infest Amy, Bernadette, Wolowitz and Koothrappali with pink eye.
S11, EP22 "The Monetary Insufficiency"
Sheldon goes to Las Vegas to win money for science; Penny and Bernadette take Amy wedding dress shopping, but her terrible choice entangles them in a web of lies.
S11, EP21 "The Comet Polarization"
Sheldon's comic book store experience changes when writer Neil Gaiman puts Stuart's store on the map; friendships are threatened when Koothrappali takes credit for Penny's astronomical discovery.
S11, EP20 "The Reclusive Potential"
A brilliant but reclusive scientist, Doctor Wolcott, invites Sheldon to his cabin in the middle of nowhere; Penny and Bernadette improvise after Amy doesn't like the tame bachelorette party they planned for her.