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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP22 "The Wildebeest Implementation"
Raj tries to cure his social anxiety; Penny spies on Leonard and his girlfriend through Bernadette.
S5, EP17 "The Rothman Disintegration"
Sheldon and his nemesis, Kripke, compete for a corner office; Penny feels uncomfortable after receiving a gift from Amy.
S6, EP4 "The Re-Entry Minimization"
Wolowitz's return from space isn't all he expected; game night becomes a gender war.
S6, EP8 "The 43 Peculiarity"
Raj and Howard try to figure out why Sheldon disappears at 2:45 every afternoon; jealousy arises in Penny and Leonard's relationship.
S10, EP14 "The Emotion Detection Automation"
Sheldon tests an MIT invention after hearing it can help him read people's emotions; Leonard finds out Penny's brother is coming to town; Raj asks his ex-girlfriends to give him dating advice.
S10, EP13 "The Romance Recalibration"
Penny thinks Leonard is taking her for granted and decides to go on a spa weekend with Amy; Wolowitz and Koothrappali try to fix a squeaky floorboard in the baby's room.
S10, EP12 "The Holiday Summation"
Sheldon and Amy visit Penny and Leonard after the holidays and tell them about their terrible trip to Texas.
S10, EP11 "The Birthday Synchronicity"
While Howard and Bernadette welcome their new baby into the world, Amy celebrates her own birthday with Sheldon.