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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S7, EP20 "The Relationship Diremption"
Sheldon has a personal crisis when he decides string theory is a waste of his time; a double date ends in embarrassment for Howard.
S4, EP10 "The Alien Parasite Hypothesis"
Amy realizes she has feelings for Penny's ex; Koothrappali and Wolowitz try to prove who would be a better superhero.
S6, EP4 "The Re-Entry Minimization"
Wolowitz's return from space isn't all he expected; game night becomes a gender war.
S6, EP5 "The Holographic Excitation"
The gang heads to Stuart's comic book store to celebrate Halloween; Leonard uses science to seduce Penny.
S12, EP8 "The Consummation Deviation"
Sheldon tries to bond with Amy's father, but when Wolowitz lures Mr. Fowler away with magic tricks, Sheldon has no choice but to bond with Mrs. Fowler; Koothrappali and Anu try to get physical for the first time.