
Kathryn Janeway is the captain of a starship that is lost in space and must travel across an unexplored region of the galaxy to find its way back home. On its way, the crew encounters different species they must deal with, but find that all their adventures only make them long for home.

The Doctor, at a loss on how to treat Lt. Torres, consults the holographic re-creation of a Cardassian war criminal; Torres learns the identity of this exobiology specialist, and refuses treatment, causing The Doctor to experience a moral quandary.

Voyager discovers a massive ocean floating in space, populated by an alien species in trouble; Tom Paris is accused of breaking with protocol.

A Devore officer asks Janeway for asylum after he intercepts Voyager to search for two families of alien refugees who have been rescued by the ship's crew.

The Doctor launches an investigation to find the person or thing that tampered with his short-term memory.