
This long-running animated comedy focuses on the eponymous family in the town of Springfield in an unnamed U.S. state. The head of the Simpson family, Homer, is not a typical family man. A nuclear-plant employee, he does his best to lead his family but often finds that they are leading him. The family includes loving, blue-haired matriarch Marge, troublemaking son Bart, overachieving daughter Lisa and baby Maggie. Other Springfield residents include the family's religious neighbor, Ned Flanders, family physician Dr. Hibbert, Moe the bartender and police chief Clancy Wiggum.

Marge's resentment takes monstrous form; Lisa tries to save the planet through murder; Homer learns he's not the man he thought he was.

Ned gains the power to foretell people's deaths; Maggie is shrunk, then swallowed by Mr. Burns; in Victorian London, Detective Eliza Simpson and her sidekick, Dr. Bartley, pursue the Muttonchop Murderer.

When Bart reads a set of Aramaic symbols, he and Lisa find themselves transported to an alternate universe; a member of Moe's gang wants to leave the life for a girl; the family is visited by former versions of themselves.

Homer wreaks havoc in Springfield; when Bart is beheaded, his body is attached to Lisa's body; things go awry at Mr. Burns' traveling circus.