
Chiropractor and single father Alan Harper lives in a beachfront house with divorced Internet billionaire Walden Schmidt, who bought the house following the untimely death of Alan's brother, Charlie. As they acclimate to their living arrangement, the tightly wound Alan finds himself taking on a mentor role with Walden, whose lifelong dependence on being taken care of has left him a bit naive. Despite his unsuccessful romantic history, Alan also tries to help Walden overcome his limited experiences with dating. Berta, a sharp-tongued, unapologetic housekeeper, is also featured in the series.

Alan's homely high-school friend (Paget Brewster) returns as a beautiful woman, and the brothers quickly begin competing for her attentions.

Walden parties with Jenny and her attractive friends; Alan's illicit affair with Lyndsey is jeopardized.

Charlie's life turns upside down when his brother and nephew move in; at the supermarket, Charlie discovers he can use 10-year-old Jake to attract women.

When Judith's pipes burst after an earthquake, Alan invites her to stay with him at Charlie's house.