
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victim was involved in a love quadrangle, giving several people motive to kill.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.