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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S6, EP6 "Fire Dot Com"
A mother puts her hope in the internet and an independent investigation to clear her name after authorities charge her with murdering her 17-month-old son in a fire considered to be intentionally set.
S3, EP12 "Broken Bond"
A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.
S6, EP23 "Sibling Rivalry"
The pornography empire cultivated by brothers Artie and Jim Mitchell crumbles when one turns up dead and his brother confesses to shooting him; investigators question whether the shooting was premeditated.
S6, EP11 "Photo Finish"
Photographs found in a dumpster lead to the killer of Los Angeles model Linda Sobek; the man claims he did not intentionally kill her despite evidence to the contrary.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.