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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP9 "The Boyfriend Complexity"
Penny asks Leonard to lie to her father (Keith Carradine); Howard, Raj and Bernadette pull an all-nighter at a telescope.
S6, EP10 "The Fish Guts Displacement"
When Amy gets sick, Sheldon tries to nurse her back to health; Wolowitz and his father-in-law plan a fishing trip.
S6, EP19 "The Closet Reconfiguration"
Howard considers whether he should open a letter from his father; Penny and Leonard host a "grown-up" cocktail party.
S11, EP23 "The Sibling Realignment"
Sheldon's mother won't attend his wedding unless he invites his brother; the Wolowitz kids inadvertently infest Amy, Bernadette, Wolowitz and Koothrappali with pink eye.
S9, EP24 "The Convergence Convergence"
Leonard's recently divorced parents and Sheldon's devoutly religious mother visit; when they are contacted about their guidance system, Wolowitz and Koothrappali think the government is after them.
S9, EP23 "The Line Substitution Solution"
Sheldon wants to go to a movie screening, so he pays Stuart to spend the day with Amy; Penny has a difficult time connecting with Leonard's visiting mother.
S9, EP22 "The Fermentation Bifurcation"
The gang runs into Penny's old boyfriend while out at a wine bar; Bernadette spends an evening with Sheldon; Koothrappali's introduction of his new girlfriend doesn't go as planned.
S9, EP21 "The Viewing Party Combustion"
During a group get-together, a minor argument between Sheldon and Leonard turns into a heated debate, leaving the rest of the gang to choose sides.