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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S3, EP18 "The Pants Alternative"
Sheldon's stage fright stands between him and a coveted award.
S11, EP23 "The Sibling Realignment"
Sheldon's mother won't attend his wedding unless he invites his brother; the Wolowitz kids inadvertently infest Amy, Bernadette, Wolowitz and Koothrappali with pink eye.
S5, EP2 "The Infestation Hypothesis"
Amy is caught in the middle when Penny and Sheldon get into an argument over a pre-owned chair; Leonard tries to make his long-distance relationship more exciting.
S5, EP3 "The Pulled Groin Extrapolation"
Amy and Leonard try to become better acquainted; Bernadette, Howard and Mrs. Wolowitz spend the weekend together.